Screening for AbdominAl Aortic AneurySmS
نویسنده
چکیده
............................................................................................................................................... 9 Svensk sammfattning................................................................................................................... 11 List of publications......................................................................................................................... 13 Abbreviations................................................................................................................................... 15 1. Background................................................................................................................................... 17 1.1 General aspects of Abdominal Aortic Aneurysm.................................................. 17 1.2 Diagnostic methods.......................................................................................................... 19 1.3 Epidemiology....................................................................................................................... 21 1.4 Natural course, growth rate and risk of rupture................................................... 23 1.5 Treatment for Abdominal Aortic Aneurysm.......................................................... 24 1.6 Population-based screening for AAA....................................................................... 27 2. Aims with this thesis................................................................................................................ 29 3. Patients and methods................................................................................................................ 31 3.1 Study designs....................................................................................................................... 31 3.2 Hospital settings in Stockholm County.................................................................... 33 3.3 Registries used in this thesis........................................................................................ 33 3.4 Patients and methods studies I and II...................................................................... 34 3.5 Patients and methods study III................................................................................... 36 3.6 Patients and methods study IV...................................................................................... 37 4. Results.................................................................................................................................................... 39 4.1 Overall results......................................................................................................................... 39 4.2 Results study I and II.......................................................................................................... 40 4.2 Results study III..................................................................................................................... 42 4.3 Results study IV.................................................................................................................... 46 5. Discussion........................................................................................................................................... 53 5.1 Screening of siblings.......................................................................................................... 53 5.2 No regional difference in AAA-prevalence in siblings....................................... 54 5.3 Participation in populations-based screening....................................................... 56 5.4 Results of surgery on screening-detected AAA’s.................................................. 57 5.5 Future perspectives............................................................................................................. 59 5.6 Strengths and limitations................................................................................................. 60 6. Acknowledgements........................................................................................................................ 63 7. References........................................................................................................................................... 67
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